Xiaolin Zi Selected Research

1,3,5,8- tetrahydroxy- 2,4- bis(3- methyl- 2- butenyl)xanthone

1/2020	Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy.
1/2013	The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell lines.

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Xiaolin Zi Research Topics

Disease

36	Neoplasms (Cancer) 02/2022 - 10/2004
11	Prostatic Neoplasms (Prostate Cancer) 11/2021 - 11/2005
9	Urinary Bladder Neoplasms (Bladder Cancer) 12/2017 - 04/2005
8	Carcinogenesis 02/2022 - 03/2012
7	Osteosarcoma (Osteogenic Sarcoma) 01/2021 - 07/2007
5	Neoplasm Metastasis (Metastasis) 10/2020 - 07/2007
4	Carcinoma (Carcinomatosis) 02/2022 - 06/2013
3	Breast Neoplasms (Breast Cancer) 03/2017 - 01/2004
3	Stomach Neoplasms (Stomach Cancer) 01/2017 - 11/2013
3	Esophageal Neoplasms (Esophageal Cancer) 12/2016 - 07/2013
2	Renal Cell Carcinoma (Grawitz Tumor) 08/2016 - 01/2016
2	Infections 06/2013 - 01/2013
1	Non-Muscle Invasive Bladder Neoplasms 02/2022
1	Adenocarcinoma 11/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2019
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2019
1	Hyperalgesia 01/2019
1	Cystitis 01/2019
1	Kidney Neoplasms (Kidney Cancer) 08/2016
1	Hyperplasia 03/2016
1	Hypoxia (Hypoxemia) 01/2016
1	Neurogenic Urinary Bladder (Bladder, Neurogenic) 10/2015
1	Retinoblastoma (Glioblastoma, Retinal) 12/2013

Drug/Important Bio-Agent (IBA)

13	Chalcone (Benzalacetophenone)IBA 02/2022 - 04/2005
9	flavokawain AIBA 02/2022 - 04/2005
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2010
6	flavokawain BIBA 01/2019 - 10/2010
4	Pharmaceutical PreparationsIBA 01/2019 - 02/2011
4	Phosphotransferases (Kinase)IBA 03/2017 - 01/2004
4	AgarIBA 08/2012 - 04/2005
3	SurvivinIBA 02/2022 - 04/2005
3	Docetaxel (Taxotere)FDA Link 11/2021 - 02/2011
3	Lysine (L-Lysine)FDA Link 01/2021 - 06/2013
3	RNA (Ribonucleic Acid)IBA 01/2021 - 04/2014
3	S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA 10/2020 - 12/2015
3	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 10/2010
3	AndrogensIBA 01/2017 - 11/2005
3	DiterpenesIBA 12/2016 - 07/2013
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2016 - 07/2013
3	CateninsIBA 08/2016 - 08/2012
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2014 - 01/2004
2	LycopeneIBA 11/2021 - 02/2011
2	Histones (Histone)IBA 01/2021 - 06/2013
2	1,3,5,8- tetrahydroxy- 2,4- bis(3- methyl- 2- butenyl)xanthoneIBA 01/2020 - 01/2013
2	xanthoneIBA 01/2020 - 01/2013
2	EnzymesIBA 01/2020 - 06/2013
2	LigandsIBA 01/2019 - 08/2011
2	Biological ProductsIBA 01/2018 - 11/2005
2	rhodiolosideIBA 12/2017 - 03/2012
2	Trastuzumab (Herceptin)FDA Link 03/2017 - 01/2004
2	Kaurane DiterpenesIBA 12/2016 - 07/2013
2	Conditioned Culture MediaIBA 08/2016 - 05/2008
2	Metformin (Glucophage)FDA LinkGeneric 03/2016 - 12/2015
2	Retinoblastoma ProteinIBA 12/2015 - 12/2013
2	Messenger RNA (mRNA)IBA 04/2015 - 03/2010
2	Small Interfering RNA (siRNA)IBA 04/2015 - 05/2008
2	jaridoninIBA 01/2015 - 07/2013
2	Hormones (Hormone)IBA 04/2014 - 10/2010
2	Biomarkers (Surrogate Marker)IBA 06/2013 - 08/2012
2	Cadherins (E-Cadherin)IBA 06/2010 - 07/2007
1	F-Box ProteinsIBA 01/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2021
1	AmidesIBA 04/2020
1	Growth InhibitorsIBA 01/2020
1	Proteasome InhibitorsIBA 01/2019
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2019
1	Death Domain ReceptorsIBA 01/2019
1	Bortezomib (Velcade)FDA Link 01/2019
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 01/2019
1	Proto-Oncogene Proteins c-mdm2IBA 01/2018
1	25-methoxydammarane-3,12,20-triolIBA 01/2018
1	GinsenosidesIBA 01/2018
1	yangoninIBA 09/2017
1	Caspase 9IBA 01/2017
1	oridoninIBA 12/2016
1	Acetylcysteine (Siran)FDA LinkGeneric 12/2016
1	Hypoglycemic Agents (Hypoglycemics)IBA 03/2016
1	Adenosine Monophosphate (AMP)IBA 03/2016
1	physapubescinIBA 01/2016
1	ResveratrolIBA 12/2015
1	AerosolsIBA 10/2015
1	Neuropilin-2IBA 04/2015
1	Cysteine (L-Cysteine)FDA Link 01/2014
1	BenzaldehydesIBA 01/2014
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2014
1	Insulin-Like PeptidesIBA 01/2014
1	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2014
1	ChalconesIBA 01/2014
1	AcetophenonesIBA 01/2014
1	3- (5- nitrofuryl)- 7- (5- nitrofurfurylidene)- 3,3a,4,5,6,7- hexahydro- 2H- indazoleIBA 11/2013
1	TriazolesIBA 11/2013
1	MethyltransferasesIBA 06/2013
1	CarcinogensIBA 06/2013
1	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2013

Therapy/Procedure

10	Therapeutics 04/2020 - 08/2011
5	Chemoprevention 02/2022 - 03/2012
3	Castration 01/2019 - 02/2011
2	Drug Therapy (Chemotherapy) 10/2020 - 07/2012
1	Cystectomy 01/2019